“RACK”-ing up the effectors

Ang-1: Tie-ing up endothelial adhesion?

"Patch"ing up our tumor signaling knowledge.

The tumor suppressor Patched1 (Ptch1) possesses well-described roles in regulating sonic hedgehog (SHH) signaling in the skin and preventing the formation of basal cell carcinomas (BCCs). In this issue, Kang et al. extend their previous work to show that a naturally occurring allele of Ptch1 found in FVB mice promotes early squamous cell carcinoma (SCC) growth without aberrant activation of the...

The Rack Space

The main result of this paper is a new classification theorem for links (smooth embeddings in codimension 2). The classifying space is the rack space and the classifying bundle is the first James bundle. We investigate the algebraic topology of this classifying space and report on calculations given elsewhere. Apart from defining many new knot and link invariants (including generalised James-Ho...

Rack Space

The main result of this paper is a new classification theorem for links (smooth embeddings in codimension 2). The classifying space is the rack space and the classifying bundle is the first James bundle. We investigate the algebraic topology of this classifying space and report on calculations given elsewhere. Apart from defining many new knot and link invariants (including generalised James-Ho...

A Trap for Capturing Arthropods ing Up Tree Bo

A simple trap is described that captures ahopods as they crawl up tree boles. Comtmcted &om metal hnnels, plastic sandwich containers, and sp imen cups, the traps can be assen~bled by one person at a rate of 5 to 6 per hour and installed in 2 to 3 nrinutes. S p i m e n colle~tion required 15 to 20 seconds per trap. In 1383, h a traps were phced on each tree. In 1994, a single trap per tree with...